The examine will examine whether or not taking atorvastatin, a drug generally used to decrease ldl cholesterol additionally referred to as Lipitor, can assist adults aged 75 and older keep their well being by stopping dementia, incapacity and coronary heart illness.
The examine, which goals to be one of many largest ever performed amongst older adults, will embrace greater than 20,000 individuals and 100 websites throughout the US. It is going to randomize individuals with out coronary heart illness or dementia to obtain both atorvastatin or placebo. Researchers will observe individuals for as much as 5 years and check their reminiscence, pondering and bodily talents, and monitor them for occasions corresponding to coronary heart assaults or strokes.
The examine is designed to make analysis participation straightforward and environment friendly. Researchers will observe individuals utilizing digital well being information, Medicare information and with telephone visits.
“PREVENTABLE is a exceptional examine for a lot of causes,” Dr. Katie Benziger, a heart specialist on the Essentia Well being St. Mary’s-Coronary heart & Vascular Middle, stated in a information launch. “Few research have targeted completely on people aged 75 or older. Whereas statins have been proven to scale back the danger of cardiovascular occasions for some sufferers, PREVENTABLE will assist us be taught whether or not they’re useful for older adults with out coronary heart illness.”
Statins are a typical identify for a bunch of medicines that assist decrease ldl cholesterol and cut back the danger of coronary heart illness and stroke.
About one in three individuals within the U.S. over the age of 75 with out coronary heart illness are taking statins. So along with studying whether or not statins can lengthen well being in older adults, the PREVENTABLE examine will assist make clear which older adults shouldn’t be taking statins.
“Sufferers typically ask me what they will do to remain wholesome and stop dementia,” Dr. Karen Alexander, a geriatric heart specialist at Duke College Medical Middle and the principal investigator for PREVENTABLE, stated within the information launch. “This examine will assist to make clear the good thing about statins for this inhabitants. That is essential to do earlier than including yet another medicine to the checklist of medicines older adults are sometimes already taking.”
For extra info, together with who can participate within the examine, contact Ryan Thiel, analysis and analysis specialist at Essentia Well being, at 218-786-8856 or Ryan.Thiel@EssentiaHealth.org.